Paris, France, Thursday, October 17, 2024, 7:30 am CET – GenSight Biologics (Euronext: SIGHT, ISIN: FR0013183985, PEA-PME eligible), a biopharma company focused on discovering and developing innovative gene therapies for retinal neurodegenerative diseases and central nervous system disorders, today announced that new scientific data and analyses on the gene therapy LUMEVOQ® will be presented at the 2024 annual meeting of the American Academy of Ophthalmology (AAO) in Chicago, Illinois (October 18-21, 2024).

Leading Leber Hereditary Optic Neuropathy (LHON) Key Opinion Leaders will provide updates on the comparison between LHON natural history, idebenone and LUMEVOQ®; on real-world experience with LUMEVOQ®; on evidence related to the contralateral effect; and on long-term outcomes from bilateral injection of LUMEVOQ®.

Poster: “Meta-analysis of Treatment Outcomes for Patients with m.11778G>A MT-ND4 Leber Hereditary Optic Neuropathy” (Poster PO004)

  • Presenter: Nancy J. Newman, MD, Emory University School of Medicine, Atlanta, Georgia, USA
  • Time: Saturday, October 19, 2024, from 9:15 – 10:15 AM CDT
  • Location: Hall A, Poster Theater

Presentation: “Efficacy and Safety of Lenadogene Nolparvovec Gene Therapy for LHON in Real-Life Settings” (PA023)

  • Presenter: Valerie Biousse, MD, Emory University School of Medicine, Atlanta, Georgia, USA
  • Session: OP04 Neuro-Ophthalmology Original Papers
  • Time: Saturday, October 19, 2024, from 2:48 – 3:00 PM CDT
  • Location: S405

Poster: “Post-Mortem Analyses with Histopathological and Molecular Assessments Following AAV2 Gene Therapy in LHON” (Poster PO093)

  • Presenter: Alfredo A. Sadun, MD, PhD, Doheny Eye Centers-UCLA, Pasadena, California, USA
  • Time: Sunday, October 20, 2024, from 9:15 – 9:45 AM CDT
  • Location: Station 2, Poster Discussion Lobby

Presentation: “Four-Year Results of Bilateral Injection of Lenadogene Nolparvovec Gene Therapy for LHON” (PA047)

  • Presenter: Patrick Yu-Wai-Man, FRCOphth, MBBS, PhD, University of Cambridge, Cambridge, England
  • Session: OP08 Retina, Vitreous Original Papers
  • Time: Sunday, October 20, 2024, from 2:48 – 2:55 PM CDT
  • Location: S405

 

Contacts